Health Effects of Beryllium Exposure: A Literature Review
Chapter 2 reviews exposure factors important for assessing health risks associated with beryllium. It includes a review of the exposure assumptions that underlie existing exposure standards, consideration of exposures in natural and anthropogenic settings, and an examination of how physiochemical characteristics and particle sizes are ...
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Federal Register :: Occupational Exposure to Beryllium
In developing its review of the preliminary health effects from beryllium exposure and assessment of risk for the NPRM, OSHA prepared a Start Printed Page 2481 pair of draft documents, entitled "Occupation Exposure to Beryllium: Preliminary Health Effects Evaluation" (OSHA, 2010, Document ID 1271) and "Preliminary Beryllium …
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The uses and adverse effects of beryllium on health
The authors emphasized the need for increased management commitment to health and safety, empowerment of employees to maintain a clean workspace, and training videos on methods of exposure risk. In a copper-beryllium alloy processing facility, workers were exposed to beryllium in the greatest concentrations exceeding 0.2 μg/m 3.
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Beryllium Toxicity
Beryllium exposure and toxicity can cause serious acute and long-term health effects, making its immediate identification and …
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Beryllium
Who is at risk from exposure to beryllium? What is Chronic Beryllium Disease (CBD)? What is beryllium sensitization? How will the beryllium rule protect workers' health? Need …
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Exposure and genetics increase risk of beryllium sensitisation …
Objectives: Beryllium sensitisation (BeS) and chronic beryllium disease (CBD) are caused by exposure to beryllium with susceptibility affected by at least one well-studied genetic host factor, a glutamic acid residue at position 69 (E69) of the HLA-DPβ chain (DPβE69). However, the nature of the relationship between exposure and carriage of the DPβE69 …
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Medical Surveillance for Beryllium‑Exposed Workers
the employee at increased risk from further airborne exposure, or any medical conditions related to airborne exposure that require further evaluation or treatment), • Any recommendations on the employee's use of PPE or respirators, • Any limitations on the employee's airborne beryllium exposure, and • Any recommendation for referral to a
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Occupational exposure to beryllium and cancer risk: A …
Exposure to fluorides and copper was highly correlated to beryllium exposure, and the results on lung cancer risk paralleled those for beryllium. An indirect adjustment for smoking was performed using the data from a survey of about 10% of workers who were employed in 1968 (this appears to be the same survey used to adjust …
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Beryllium exposure: dermal and immunological considerations …
Objective: People exposed to beryllium compounds are at increased risk of developing beryllium sensitization and chronic beryllium disease (CBD). The purpose of this short communication is to present information regarding the potential importance of skin exposure to beryllium, an exposure and alternate immune response pathway to the …
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Summary | Health Effects of Beryllium Exposure: A …
The first is to provide a review of the scientific literature on beryllium, and the second will expand more critically on the review in considering the maximum chronic inhalation exposure levels that are unlikely to produce adverse health effects, in estimating carcinogenic risks, and in providing guidance on testing methods for surveillance ...
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Managing Health Effects of Beryllium Exposure
Managing Health Effects of Beryllium Exposure - NCBI Bookshelf. Beryllium is a lightweight metal that is used for its exceptional strength and high heat-absorbing capability. Beryllium and its alloys can be found in many important technologies in the defense and aeronautics industries, such as nuclear devices, satellite systems, radar systems ...
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ToxGuide for Beryllium
risk for beryllium exposure. Workers' family members may also be exposed to beryllium from contaminated clothing. Toxicokinetics and Biomonitoring Toxicokinetics Inhalation is the primary route of beryllium absorption in humans, but data on the rate and extent of absorption of inhaled beryllium in humans are limited.
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CCOHS: Beryllium
Exposure to beryllium can lead to sensitization - an allergic-type response. Not all workers will develop sensitivity to beryllium. In most cases, a worker may be sensitized but there are no health symptoms. A blood test called beryllium lymphocyte proliferation test (BeLPT) can measure how blood cells react to beryllium. This test can …
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Guidance on Medical Surveillance for Beryllium Exposed …
Workers sensitized to beryllium are at risk for developing CBD and need continuing medical follow-up. CBD is diagnosed when medical screening identifies a beryllium exposure history and characteristics in the lung that indicate CBD. 5 Other tests may include a low-dose CT scan, which is used for diagnosing lung cancer.
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Preventing Sensitization and Disease from Beryllium …
low as possible, since a safe exposure limit for beryllium has not been determined. Monitor airborne beryllium concentrations to document the effectiveness of efforts to reduce . airborne exposures. Inform workers about the risks of beryllium sen-sitization, chronic beryllium disease, and lung cancer, and the proper procedures for …
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Beryllium
Exposure to beryllium via inhalation of airborne beryllium or skin contact with beryllium-containing dust, fume, mist, or solutions can cause health effects. Under OSHA's beryllium standards (29 CFR 1910.1024; 29 CFR 1915.1024; 29 CFR 1926.1024) …
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Beryllium, Cadmium, Mercury, and Exposures in the Glass …
This volume evaluates the carcinogenic risk to humans posed by exposure to selected metals and their compounds. Separate monographs are presented for beryllium and beryllium compounds, cadmium and cadmium compounds, and mercury and inorganic and methylmercury compounds. Because several metallic salts and pigments are used in the …
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Final Toxicological Profile Published for Beryllium | AIHA
OSHA estimates that 62,000 workers are potentially exposed to beryllium in more than 7,000 workplaces in the United States. Workers in the beryllium manufacturing, fabricating, or reclaiming industries are at high risk of exposure to the metal, and most significant beryllium exposures occur in the workplace, according to an ATSDR …
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Biomonitoring Summary | CDC
The effects of occupational exposure to beryllium depend on the concentration of beryllium in the inhaled air and the duration of air exposure. Air levels greater than 100 µg/m3 can result in erythema and edema of the lung mucosa, which produces pneumonitis. ... Maier L. Genetic and exposure risks for chronic beryllium disease. Clin ChestMed ...
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What Are the U.S. Standards for Beryllium Exposure?
Table 1 shows standards and regulations for beryllium. The occupational exposure limit of 2.0 micrograms per cubic meter (µg/m 3) of air for an 8-hour work shift for beryllium has been used in the workplace since the late 1940s.However, recent research has shown that the 2.0 mg/m 3 standard is not protective (For example, see the ACGIH standards). ). …
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Beryllium | ToxFAQs™ | ATSDR
People working or living near beryllium industries have the greatest potential for exposure to beryllium. Lung damage has been observed in people exposed to high levels of beryllium in the air. About 1-15% of all people occupationally-exposed to beryllium in air become sensitive to beryllium and may develop chronic beryllium disease (CBD), an …
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Introduction
Chapter 2 reviews exposure factors important for assessing health risks associated with beryllium. It includes a review of the exposure assumptions that underlie existing exposure standards, consideration of …
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Summary
Thus, the committee considered risks posed by beryllium exposure broadly to include all forms of beryllium. The immunopathogenic mechanisms underlying BeS and progression to CBD have been …
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Managing Health Effects of Beryllium Exposure.
It is well established that beryllium causes sensitization (beryllium sensitization, BeS) and chronic beryllium disease (CBD). This chapter assesses the risk of those conditions posed by occupational exposure …
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Health Effects of Beryllium Exposure: A Literature Review
As described by Kreiss et al. (2007), its diverse uses may put a growing number of workers at risk of beryllium exposure. Henneberger et al. (2004) relied on sampling compliance data from the Occupational Safety and Health Administration (OSHA) to estimate that 134,000 U.S. workers are potentially exposed to beryllium; however, Kreiss et al ...
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About Beryllium | Department of Energy
Exposure to beryllium particles can cause a serious illness in certain people. This illness is chronic beryllium disease, or CBD-an irreversible and sometimes fatal scarring of the lungs. Medical studies show that even small amounts of beryllium particles of a size that can be breathed deeply into the lungs may trigger an allergy-like ...
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Beryllium Toxicity: Patient Education Care Instruction …
Exposure to beryllium can affect the lungs and/or skin. However, not everyone will develop health effects from beryllium exposure. People who work closely with beryllium as part of …
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Berylliosis (Chronic Beryllium Disease): Symptoms
Most studies show that between 2% and 6% of workers who are susceptible to beryllium sensitization will develop the disease after exposure to beryllium. Many …
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Potential Health Effects from Exposure to Cube
Explore and download in-depth case studies, insightful white papers, detailed product information, and technical documents.
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Beryllium Toxicity: Patient Education Care Instruction Sheet
Once a person has been exposed to beryllium, they have a lifelong risk of developing disease even if exposure stops. Beryllium usually affects the respiratory system, although it can affect other parts of the body as well. Listed below are different types of illnesses or health effects associated with beryllium.
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